This book provides a summary of the various aspects of corneal transplantation — the clinical, experimental (including multimedia display of the surgical techniques), immunological, therapeutic and prosthetic components — in one volume. The interested specialist in one field can thus have access to information from the other fields and develop a broad concept of the challenges to be faced in achieving the ultimate goal, i.e. an optically clear, visually satisfactory, functioning corneal graft which is tolerated in the long term without the need for systemic immunosuppression. A second purpose of the book is to provide information regarding current immunological concepts of the process of corneal graft rejection. In particular, recent work in the fields of innate versus adaptive immunity, novel therapeutics and corneal xenografts is presented.