The clinical applications of diffusion-weighted MR imaging (DW-MRI) in the body are rapidly evolving. This volume highlights state-of-the-art techniques for performing DW-MRI measurement in the body and addresses important practical issues. Key points are highlighted that will help radiologists and technologists to acquire high-quality images for disease assessment and to adapt the technique to their own clinical practice or research. The major clinical applications of DW-MRI in the body, both oncological and non-oncological, are extensively illustrated, providing readers with a broad insight into the growing uses of the technique. The final section addresses future developments, considering the potential importance of the technique in relation to drug development and the ways in which DW-MRI might be combined with other functional imaging techniques to further improve disease assessment.