Antifreeze proteins enable organisms to avoid freezing under extreme conditions. The greatest diversity of known antifreeze proteins is in teleost fish and much work has gone into the understanding of these proteins and their applications.Antifreeze proteins are an exciting model system for the study of protein–surface(ice) interaction. They have served as unique model structures in protein science and they are also useful tools in the study of fish physiology and behavior. Their emergence in some fish species has even provided a rare glimpse of de novo protein evolution in action.To cover the diverse aspects of fish antifreeze study, a wide spectrum of researchers have been selected to write clear and comprehensive articles on different areas of antifreeze research. This book should be a very useful and informative resource for life science researchers.