Cancer touches the lives of millions worldwide each year. This is reflected not only in well publicised mortality statistics but also in the profound, though much more difficult to measure, effects of cancer on the health-related quality of life, economic status and overall wellbeing of patients and their families. In 2001, the U.S. National Cancer Institute established the Cancer Outcomes Measurement Working Group to evaluate the state of the science in measuring the important and diverse impacts of this disease on individuals and populations. The findings and recommendations of the Working Group's 35 internationally recognised members are reported in this book, lucidly written and accessible to both researchers and policy makers in academia, government and industry. This volume provides the most penetrating yet practical discussion to date of alternative approaches for comprehensively measuring the burden of cancer and the effectiveness of preventative and therapeutic interventions.