The prevention of harm from drug use, both legal and illegal, is a major concern to government departments and clinicians throughout the world. Recently, much new research has been conducted regarding global levels and patterns of drug-related harm, on common risk factors with other social problems (e.g. mental health, crime) and on the effectiveness of wide range of intervention strategies. There is a need to summarise and synthesise this new knowledge for use in a range of disciplines. Preventing Harmful Substance Use offers the most comprehensive and up-to-date advice available on the prevention of drug and alcohol abuse. Contributors provide authoritative, science-based reviews of knowledge on their areas of expertise, and make clear recommendations for the future of prevention policy and practice. A final section draws the work together and offers a framework for an integrated science of prevention.