The outcome of recent clinical trials in osteoporosis was the impetus for this volume. In these studies of two bisphosphonates, an interaction between bone mineral density (BMD) and the treatment effect was seen, such that these agents appeared to lose their effect as BMD increased. To practitioners this is counter-intuitive. Why should treatment work and not prevention? This book uses a solid evidence base to explore such issues, without limiting itself to specialist concerns. It tackles other facets of the disease as well, such as the economic aspects. Prevention and Treatment of Osteoporosis in the High-Risk Patient is intended for physicians of all specialties who see patients who have or might be at risk of developing osteoporosis.