In this book, the author announces the class of problems called “entropy of knots” and gives an overview of modern physical applications of existing topological invariants.He constructs statistical models on knot diagrams and braids using the representations of Jones–Kauffman and Alexander invariants and puts forward the question of limit distribution of these invariants for randomly generated knots. The relation of powers of corresponding algebraic invariants to the Lyapunov exponents of the products of noncommutative matrices is described. Also the problem of conditional joint limit distributions for “brownian bridges” on braids is discussed. Special cases of noncommutative groups PSL(2,R), PSL(2,Z) and braid groups are considered in detail.In this volume, the author also discusses the application of conformal methods for explicit construction of topological invariants for random walks on multiconnected manifolds. The construction of these topological invariants and the monodromy properties of correlation function of some conformal theories are also discussed.The author also considers the physical applications of “knot entropy” problem in various physical systems, focussing on polymers.