This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities. Clinical trial concepts and detailed treatment protocols are also presented. Part I describes biological and pharmacological fundamentals for therapy and introduces laboratory models for isolated limb and organ perfusion. Topics introduced in Part II include interventional radiotherapy, surgical strategies, regional thermotherapy, radiofrequency thermal ablation, cryoablation, nanocarriers and drug delivery, and local gene therapy for cancer. Highlights of Part III include regional chemotherapy of primary and metastatic liver tumors and focal liver ablation techniques in primary and secondary liver tumors. Regional Cancer Therapy is essential reading for researchers and clinicians engaged in seeking advanced therapeutic options for cancer patients worldwide.