This volume will evaluate the carcinogenic risk to humans posed by infection with human papillomaviruses (HPVs). To date, more than 70 HPV types have been identified, of which over 15 have been reported in cervical cancer biopsies. Worldwide, cervical cancer is the second most common cancer in women; approximately 500,000+ new cases are diagnosed each year. Although investigations of cervical cancer are most abundant, the report also considers the possible involvement of HPV infection in cancers at other site of the human body. The rapid advances in papillomavirus biology and vaccine development have surpassed all current summaries of the field.