Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis


Closing a gap in the literature, this is the only book series in 6 volumes to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, this series is a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures.Volume 1: Origins and Synthesis of Amino AcidsVolume 2: Modifi ed Amino Acids, Organocatalysis and EnzymesVolume 3: Building Blocks, Catalysis and Coupling ChemistryVolume 4: Protection Reactions, Medicinal Chemistry, Combinatorial SynthesisVolume 5: Analysis and Function of Amino Acids and PeptidesVolume 6: Peptide Natural Products and Amino Acid Chemistry DevelopmentThe fourth volume in this six-volume series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described.

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